Principle of CAPS and dCAPS Markers

Maxam-Gilbert Sequencing Method is chemical sequencing method based on nucleotide specific chemical modifications and subsequent DNA cleavage to manually sequence (200–300) bp, Sanger Sequencing Method is enzymatic sequencing method based on selective incorporation of chain-terminating nucleotides during DNA synthesis to manually or automatically sequence up to 1000 bp, Next Generation Sequencing Method use parallel sequencing platforms to sequence multiple samples in parallel and sequence massively fragments at once, First Generation Sequencing include Maxam-Gilbert and Sanger Sequencing Methods, Second Generation Sequencing contain platforms of NGS Method (Watch Related Video in #geneticteacher) #geneticteacher