Functions of Taq DNA Polymerase in PCR Reaction

Mitotic Catastrophe, is a malfunction of any checkpoints at G1-Phae, S-Phase, G2-Phase and M-Phases of the cell cycle, so it defines as the failure to arrest the cell cycle before or at mitosis resulting abnormal chromosome separation, which leads to generate aneuploidy cells (cell containing abnormal chromosome numbers), thus, mitotic catastrophe may be regarded as one of the mechanisms contributing tumor cell development #geneticteacher